Bovine tunica albuginea conserved in honey as xenograft for cystoplasty in rats

ABSTRACT: Urinary bladder damages leading to few viable tissue available might demand a challenging reconstructive surgery. In this context, biomaterials are valid alternatives for reconstruction. This study evaluated the bovine tunica albuginea fragment as graft material cystoplasty in rats and honey-preserved implant viability.Thirty Wistar were assigned two groups: (1) test group (T) with circular 1.0-cm-diameterbovine application apex region by continuous absorbable (Polyglactin 910 5-0) suture stitching of all layers (2) simulation (S) which animals underwent only partial cystectomy. addition, each these groups was further divided into three subgroups according euthanasia period on post-surgery day 7, 15 30.Two had self-limiting hematuria at postsurgical period. At necropsy, frequent crystals adhesion peritoneum observed. histopathological evaluation, from T euthanized 15th postoperative disorganization initial muscle development, while 30th showed complete urothelization. Urothelization pattern similar both groups. Moreover, muscular layer formation present groups, but more evident S animals. Nevertheless, inflammatory infiltrate neovascularization remarkably intense rats.It be concluded that successful repairing rats’ bladder, being good biomaterial option urinary vesicle